By using Mifeprex, one can end an early pregnancy by blocking the female hormone progesterone. It blocks a hormone needed for pregnancy to continue. It is not approved for ending later pregnancies. This pill can be taken as an alternative to a surgical abortion.
Mifeprex is a synthetic steroid. It is also known as RU-486, the early option pill for medical abortion. While it has been used for many years in Europe, Mifeprex has only been available for use in the United States since the U.S. Food and Drug Administration (FDA) approved it in 2000 for use in abortion. More than 37,000 abortions were performed using the pill in the first six months of 2001.
The lack of progesterone makes the uterus shed its lining, which causes bleeding similar to a menstrual period. Three days after taking mifepristone, women are given a second drug, misoprostol, to cause uterine contractions that expel the contents of the uterus. Most women are able remain in their own home while they pass the fetus.
How the Mifeprex should be taken :
Day 1 :-
- Read the Medication Guide and discuss the benefits and risks of using Mifeprex.
- Sign the Patient Agreement.
- After getting a physical exam, swallow 3 tablets of Mifeprex.
Day 3 :-
- If you are still pregnant, take 2 misoprostol tablets.
- Misoprostol may cause cramps, nausea, diarrhea, and other symptoms.
- Your provider may send you home with medicines for these symptoms.
Day 14 :-
- You must return to the provider about 14 days after you have taken Mifeprex to be sure you are well and that you are not pregnant.
- Your provider will check whether your pregnancy has completely ended. If it has not ended, there is a chance that there may be birth defects.
- If you are still pregnant, your provider will talk with you about the other choices you have, including a surgical procedure to end your pregnancy.
Possible side effects of Mifeprex :
All medicines may cause side effects, but many people have no, or minor side effects. The most COMMON side effects are-
- Back pain; chills/shaking; diarrhea; headache; nausea; stomach (menstrual-like) pain and/or cramping; tiredness; vaginal bleeding or discharge; vomiting.
- Severe allergic reactions (rash; hives; itching; difficulty breathing,etc.); fainting; fast heartbeat.
- Fever (100.4 degrees or higher).
- Heavy vaginal bleeding (enough to soak through 2 thick full-size sanitary pads per hour for 2 straight hours, or if you are concerned about heavy bleeding); pelvic pain or tenderness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Avoid Mifeprex if :
- One is allergic to any ingredient in Mifeprex, Misoprostol or similar medicines.
- You are taking Warfarin, Heparin, or prednisone, dexamethasone.
- You have an intrauterine device (IUD) in place.
- You have an ectopic pregnancy.
- You have chronic adrenal failure or Addison disease.
- You have bleeding problems or certain blood problems (porphyria).
- You have an undiagnosed growth in the abdomen.
- You do not understand the effects of Mifeprex or the follow-up treatment procedures or you are unable to comply with the instructions given by your health care provider.
Safety Information :
Be sure to contact your provider promptly if you have any of the following –
Heavy Bleeding :-
Contact your provider right away if you bleed enough to soak through two thick full-size sanitary pads per hour for two consecutive hours or if you are concerned about heavy bleeding.
Abdominal Pain or “Feeling Sick” :-
If you have abdominal pain or discomfort, or you are “feeling sick”, including weakness, nausea, vomiting, or diarrhea, with or without fever, for more than 24 hours after taking Misoprostol, you should contact your provider without delay.
If your fever which is at 100.4°F or higher, persists for more than 4 hours, you should contact your provider. Fever may cause serious infection or another problem.
Follow your ‘;Medication Guide’; Properly :-
Always carry the Medication Guide along with you, whenever you go to an emergency room or another health care provider. In some cases, you may advise a surgery if Mifeprex does not cause its effect. Discuss with your doctor for more information.